Tripeptide GHK against inflammation

New researches have confirmed the ability of tripeptide GHK to suppress inflammatory reactioins. Both, the tripeptide and its complexes with copper (GHK-Cu) inhibited the secretion of inflammatory cytokine interleukin-6, and at that were active in very low concentrations – from 1 nanomole to 1 micromole.

In order to create conditions, similar to those, existing in inflamed skin, the already known inflammatory cytokine – tumor necrosis factor alpha (TNF-alpha)  was injected in skin fibroblasts. This has led to a significant increase in the secretion of other inflammatory cytokine – interleukin-6.

However when immediately after TNF-alpha to fibroblasts was added tripeptide or its complex with copper, increased secretion of IL-6 did not happen at all. Thus both GNK and GNK-Cu tirned to be able to block the chain of reactions, that developed during inflammation.

The authors believe, that tripeptide GNK which is currently is one of the popular anti-aging ingredients can be used as an anti-inflammatory agent.


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