Tripeptide GHK against inflammation
New researches have
confirmed the ability of tripeptide GHK to suppress inflammatory reactioins. Both, the tripeptide and its complexes with copper
(GHK-Cu) inhibited the secretion of inflammatory cytokine interleukin-6, and at that were active in very low concentrations
– from 1 nanomole to 1 micromole.
In order to create conditions, similar to those, existing in inflamed skin,
the already known inflammatory cytokine – tumor necrosis factor alpha (TNF-alpha) was injected in skin fibroblasts.
This has led to a significant increase in the secretion of other inflammatory cytokine – interleukin-6.
when immediately after TNF-alpha to fibroblasts was added tripeptide or its complex with copper, increased secretion of IL-6
did not happen at all. Thus both GNK and GNK-Cu tirned to be able to block the chain of reactions, that developed during inflammation.
The authors believe, that tripeptide GNK which is currently is one of the popular anti-aging ingredients can be
used as an anti-inflammatory agent.