Tripeptide GNK-Cu renders harmless of
Copper is an essential element in living organisms, but free ions of copper are toxic and can accelerate the
process of aging, increasing oxidative damage to cells. Copper is necessary for the synthesis of collagen and proper operation
of dozens of important enzymes in skin, including the main antioxidant enzymes – superoxide anion dismutase (SOD). Therefore,
substances that can deliver copper to the skin cells improve the skin condition. However, on condition that the copper is
neutralized, that is not able to enhance the oxidative reaction.
The most popular carrier of copper in cosmetology
is a copper-binding peptide GHK, but until recently a lot of arguments flared up around this peptide, whether it is really
able to neutralize copper, or copper-related peptide can still damage the skin. Recently a detailed investigation have been
carried out showing that copper, complexed with GHK (GHK-Cu), is not involved in oxidative reactions and does not damage
the skin. Herewith GHK-Cu is able to quickly transfer copper to other peptides and proteins, including those enzymes that
are in need of copper. Thus, it was confirmed that the complex GHK-Cu is an ideal transporter of copper to skin.